CBD Gummies - anyone use them?

[Martin6469]

cosmo: You might try low-dose melatonin for sleep. The correct dose is 0.25mg a half-hour before bedtime, then when you wake up later, put another 0.25mg under your tongue and lay back down. Repeat this every time you wake up as long as two hours have elapsed between doses, up until a total of 1mg has been used.

You have to find 1mg tablets and split them into four pieces; most drugstore melatonin is much-too-high dosages.

More than 0.25mg within a two-hour period will saturate your receptors, and desensitize them, and nothing will happen.

[CanGetItUpButNotOff]

More than 0.25mg within a two-hour period will saturate your receptors, and desensitize them, and nothing will happen.

This is the first I've heard of this. I take 10mg nightly and can't couch for its effectiveness. Do you have a citation you can provide? Thanks.

[Martin6469]

This was an MIT study in the 1990s, when melatonin first came out. Sorry, I didn't save the study. ConsumerLab.com has some low-dose recommendations, but not exactly my recommendations of 0.25mg.

Drugstores sell enormous doses, taking advantage of the common theory that more is more, but with melatonin, more is less. If you're taking 10mg, you need to go off cold turkey for a week to reset your receptors.

[keanny454]

I know this was posted a while back, but high doses of CBD can definitely cause that kind of numbness or delayed response. I had similar issues with shop-bought edibles for my back, so I moved to a clinical prescription. I use a specific oil high in terpinolene now because it helps with the nerve pain without that heavy "blocked" feeling.